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1.
Am J Case Rep ; 25: e942706, 2024 Mar 10.
Artigo em Inglês | MEDLINE | ID: mdl-38512480

RESUMO

BACKGROUND Hypertrophic scars occur when there is an excessive wound-healing response in the skin. Fractional, or fractionated, carbon dioxide (CO2) laser therapy uses narrow shafts of light to smooth the skin surface and stimulate dermal collagen, which tightens the skin. This case report describes a 57-year-old woman with a traumatic hypertrophic scar of the face treated with fractional carbon dioxide laser therapy. The purpose of this case report was to highlight the role of fractional CO2 laser therapy in treatment of a facial traumatic hypertrophic scar in a patient after a motor vehicle crash. CASE REPORT A 57-year-old female patient presented with a hypertrophic, rigid, post-traumatic scar on the left side of her face following a motor vehicle crash. For the hypertrophic scar removal, the patient underwent 1 treatment session with fractional CO2 laser using the µ-Scan DOT scanning system. After 1 laser treatment session, the photographic documentation, which permits monitoring the treatment's effectiveness in esthetic improvement, showed a significant improvement in scar texture and color. In addition, a significant reduction in scar height was observed following laser therapy. Fractional laser treatment with the device was very well tolerated by the patient, who reported no pain or discomfort, complications, or adverse effects either during treatment or in the follow-up period (3 months). CONCLUSIONS This report demonstrates the cosmetic application of fractional carbon dioxide laser therapy in a case of hypertrophic scar with the use of an effective therapeutic protocol that did not require the use of suturing.


Assuntos
Cicatriz Hipertrófica , Terapia a Laser , Feminino , Humanos , Pessoa de Meia-Idade , Cicatriz Hipertrófica/radioterapia , Cicatriz Hipertrófica/cirurgia , Cicatriz Hipertrófica/etiologia , Cicatriz/complicações , Dióxido de Carbono , Resultado do Tratamento , Hipertrofia/etiologia , Terapia a Laser/efeitos adversos
2.
J Cancer Res Ther ; 20(1): 163-166, 2024 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-38554315

RESUMO

OBJECTIVE: Keloids and hypertrophic scars are benign fibroproliferative lesions that occur as a result of skin injury. Postoperative radiation therapy is used to reduce the recurrence rate because of the high recurrence rate with surgical treatment alone. This study aimed to identify the risk factors for recurrence after postoperative electron beam radiotherapy. MATERIALS AND METHODS: Patients with keloid or hypertrophic scars with at least one lesion and who underwent postoperative electron beam radiotherapy at our institution from June 2013 to March 2022 were included in the study, while patients with a follow-up period of fewer than three months were excluded. RESULTS: A retrospective analysis was performed on 94 lesions in 81 patients. Exactly two years after the treatment, the actuarial local control rate was 86.4%. The chest wall, shoulder, and suprapubic area were identified as high-risk recurrence sites. Compared to other body sites, these sites had significantly lower local control rates (two-year local control rates: 75.5% vs. 95.2%, P = 0.005). After multivariate analysis, treatment site (P = 0.014), male gender (P = 0.019), and younger age (P = 0.029) were revealed to be statistically significant risk factors for local recurrence. Risk factors for keloid recurrence after postoperative electron beam radiotherapy were therefore identified. CONCLUSION: This result could be used for follow-up and as a determinant for the optimal dose/fractionation of postoperative radiotherapy.


Assuntos
Cicatriz Hipertrófica , Queloide , Humanos , Masculino , Queloide/etiologia , Queloide/radioterapia , Queloide/cirurgia , Cicatriz Hipertrófica/etiologia , Cicatriz Hipertrófica/radioterapia , Cicatriz Hipertrófica/cirurgia , Estudos Retrospectivos , Elétrons , Fatores de Risco , Recidiva , Resultado do Tratamento
3.
Lasers Med Sci ; 39(1): 69, 2024 Feb 20.
Artigo em Inglês | MEDLINE | ID: mdl-38376542

RESUMO

The tendency to use less-invasive laser-based methods with far more obvious effectiveness has been taken into consideration today for improvement of burning scars. The present study thus aimed to assess the efficacy of two laser-based techniques including pulsed dye laser (PDL) and ablative fractional CO2 laser (AFCL) and its combination on improving different aspects of burning scars regardless of the types of scar as hypertrophic or keloid scars. This randomized single-blinded clinical trial was performed on patients suffering hypertrophic or keloid burning scars. The patients were randomly assigned into three groups scheduling for treatment with PDL alone, AFCL alone, or its combination. All patients were visited before and 40 days after the last treatment session, and their scars were assessed. In all groups, significant improvement was revealed in the Vancouver scar scale (VSS) score, the color of scar, vascular bed in the scar, the and height of scar and its pliability; however, the improvement in each item was more highlighted in the group receiving a combination therapy with PDL and AFCL techniques. In this regard, the highest improvement was found in vascular bed and pliability in the combination therapy group as compared to other groups. Although the superiority of the combined group was not statistically significant, due to the high percentage of improvement in total VSS and most of its indicators, it can be clinically significant. The efficacy of the treatment protocols was different considering subgroups of mature and immature scars (less than 1 year), so that more improvement in pliability of scar, vascularity, and color of scar was found in the group scheduling for PDL + AFCL as compared to those who were treated with PDL alone in immature scar group but not in mature scar group. Combined treatment can be much more effective in improving the appearance and pathological characteristics of scars than each individual treatment. This effectiveness can be seen mainly in immature scars.


Assuntos
Queimaduras , Cicatriz Hipertrófica , Queloide , Lasers de Corante , Humanos , Dióxido de Carbono , Lasers de Corante/efeitos adversos , Cicatriz Hipertrófica/radioterapia , Cicatriz Hipertrófica/cirurgia , Hipertrofia , Queimaduras/complicações , Satisfação Pessoal
4.
Skin Res Technol ; 30(2): e13605, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-38332516

RESUMO

OBJECTIVE: To evaluate and explore the efficacy of CO2 fractional laser in treating post-burn hypertrophic scars in children through Meta-analysis. METHODS: English databases (PubMed, Web of Science and The National Library of Medicine), as well as Chinese databases (China National Knowledge Infrastructure and Wanfang Data) were searched. RevMan 5.3 software was used to data analysis. RESULTS: A total of 10 pieces of literature were included, involving 413 children. Meta-analysis showed that: (1) The average Vancouver Scar Scale after surgery was significantly lower than that before surgery [weight mean difference (WMD) = -3.56, 95% confidence interval (CI):-4.53,-2.58, p < 0.001]; (2) After CO2 fractional laser, pigmentation [WMD = -0.74, 95% CI:-1.10,-0.38, p < 0.001], pliability [WMD = -0.92, 95% CI:-1.20,-0.65, p < 0.001], vascularity [WMD = -0.77, 95% CI:-1.09,-0.46, p < 0.001], height [WMD = -0.57, 95% CI:-0.95,-0.19, p < 0.001] were improved compared with those before surgery. (3) The average Visual Analogue Scale (VAS) after surgery was significantly lower than that before surgery [WMD = -3.94, 95% CI:-5.69,-2.22, p < 0.001]. (4) Both Patient and Observer Scar Assessment Scale (POSAS)-Observer [WMD = -3.98, 95% CI:-8.44,0.47, p < 0.001] and POSAS-Patient [WMD = -4.98, 95% CI:-8.09,-1.87, p < 0.001] were significantly lower than those before surgery. (5) Erythema and vesicles were the most common complications after CO2 fractional laser therapy, with an incidence of 4.09%. CONCLUSION: CO2 fractional laser is beneficial to the recovery of hypertrophic scar after burn in children, and can effectively improve the scar symptoms and signs in children, with desirable clinical efficacy.


Assuntos
Cicatriz Hipertrófica , Lasers de Gás , Criança , Humanos , Cicatriz Hipertrófica/etiologia , Cicatriz Hipertrófica/cirurgia , Cicatriz Hipertrófica/patologia , Cicatriz/etiologia , Cicatriz/cirurgia , Dióxido de Carbono , Estudos Prospectivos , Resultado do Tratamento , Lasers de Gás/uso terapêutico
5.
Medicine (Baltimore) ; 103(3): e37005, 2024 Jan 19.
Artigo em Inglês | MEDLINE | ID: mdl-38241575

RESUMO

RATIONALE: A huge hypertrophic scar formation secondary to chronic ingrown toe nail mimicking tumor is a rare disease. It is not only causing concerns cosmetically, but also hindering normal daily activities physically and socially. In this paper, we present an unusual case of bilateral ingrown nails with different phases. One resulted in a large hypertrophic scar caused by stimulation from secondary to chronic ingrown nail. PATIENT CONCERNS AND DIAGNOSIS: A 44-year-old man with a huge mass (7 × 4 × 8.5 cm) in his right great toe and inflamed ingrown nail in his left great toe visited the clinic. The mass in the right toe showed an irregular and bizarre shape with a stellate ulcer (2 × 2 cm) at the distal end. After removing an ingrown nail 3 years ago with minor repetitive trauma, self-managed wound has grown into a tumor-like mass, resulting in intolerable discomfort. In gross appearance, a stalk appeared to originate from the lateral side of the nail bed with the ingrown nail in the great toe showing inflamed medial and lateral gutter and causing redness and tenderness. Huge hypertrophic scar formation secondary to chronic ingrown toe nail mimicking tumor is a rare disease that is not only causing a cosmetic concern, but also hindering normal daily activities physically and socially. INTERVENTION AND OUTCOMES: Excisional biopsy was performed for both great toes. Biopsy confirmed chronic ulcerative inflammation with a hypertrophic scar. The resection site healed and persisted well at 12 months after surgery. CONCLUSION: Our unusual case suggests that the natural course of an untreated ingrown toe nail may result in hypertrophic scar extending far to mimic tumorous conditions.


Assuntos
Cicatriz Hipertrófica , Hallux , Unhas Encravadas , Neoplasias , Adulto , Humanos , Cicatriz Hipertrófica/diagnóstico , Cicatriz Hipertrófica/etiologia , Cicatriz Hipertrófica/cirurgia , Unhas/cirurgia , Unhas Encravadas/complicações , Unhas Encravadas/patologia , Unhas Encravadas/cirurgia , Neoplasias/complicações , Doenças Raras/patologia , Dedos do Pé/cirurgia , Masculino
7.
J Med Case Rep ; 17(1): 518, 2023 Dec 18.
Artigo em Inglês | MEDLINE | ID: mdl-38105259

RESUMO

BACKGROUND: The changes in body image caused by breast deformities and postoperative pain have a detrimental influence on the physical and mental health of patients with breast cancer. The postoperative quality of life (QOL) of these patients reduces significantly owing to the changes in the breast, an organ unique to women, that occur following breast cancer surgery. CASE PRESENTATION: This case report presents the case of a Asian woman in her early 40 s with postoperative hypertrophic scarring and contraction of the scar following mastectomy; the patient presented with decreased range of motion of the upper arm, hyperpigmentation from radiation burns, changes in breast shape, and chronic pain. The patient received a combination therapy comprising Basalt Stone Treatment and the application of horse placenta extract. As a result of a total of eight sessions conducted once every two weeks, the patient's pain and scar improved. No adverse events were observed after the therapy. CONCLUSION: Combination therapy with Basalt Stone Treatment and horse placenta extract improved the chronic pain and scar after breast cancer surgery.


Assuntos
Neoplasias da Mama , Dor Crônica , Cicatriz Hipertrófica , Humanos , Feminino , Animais , Cavalos , Gravidez , Neoplasias da Mama/cirurgia , Mastectomia/efeitos adversos , Qualidade de Vida , Dor Crônica/tratamento farmacológico , Dor Crônica/etiologia , Cicatriz Hipertrófica/etiologia , Cicatriz Hipertrófica/patologia , Cicatriz Hipertrófica/cirurgia , Placenta/patologia
8.
Drug Discov Today ; 28(11): 103801, 2023 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-37858631

RESUMO

Scars are an inevitable natural outcome of most wound healing processes and affect skin functions, leading to cosmetic, psychological and social problems. Several strategies, including surgery, radiation, cryotherapy, laser therapy, pressure therapy and corticosteroids, can be used to either prevent or treat scars. However, these strategies are ineffective, have side effects and are typically expensive. Microneedle (MN) technology is a powerful, minimally invasive platform for transdermal drug delivery. This review discusses the most recent progress in MN-mediated drug delivery to prevent and treat pathological scars (hypertrophic and keloids). A comprehensive overview of existing challenges and future perspectives is also provided.


Assuntos
Cicatriz Hipertrófica , Queloide , Terapia a Laser , Humanos , Cicatriz Hipertrófica/patologia , Cicatriz Hipertrófica/cirurgia , Queloide/patologia , Cicatrização , Crioterapia
9.
Ann Plast Surg ; 91(6): 715-719, 2023 Dec 01.
Artigo em Inglês | MEDLINE | ID: mdl-37856225

RESUMO

ABSTRACT: Hypertrophic scarring, characterized by excessive scar tissue formation, is a debilitating outcome that significantly impairs physical and psychosocial recovery after burn injury. Hypertrophic scarring affects a substantial proportion of burn survivors, with reported prevalence as high as 70%. Fractional CO 2 laser (FCL) therapy, a therapy commonly used in acne scar treatment or skin rejuvenation, has become popular in treating hypertrophic scars. Little is known regarding FCL's adverse events for burn scar treatment. We hypothesize that FCL is a safe treatment modality with minimal adverse events in the management of hypertrophic burn scars. This is a retrospective chart review of adverse events after FCL at 2 centers within a single institution. Burn patients undergoing FCL between May 1, 2019, and June 1, 2021 were included. Demographics, injury etiology, laser treatment details, and adverse events were collected. A total of 170 patients, 77 (45.3%) males and 93 (54.7%) females, underwent 544 FCL therapies for burn scars. The average number of treatments per patient was 3 ± 2.23, with a range of 1 to 17 sessions. From the total 544 laser therapy sessions, 13 adverse events (2.4%) were reported. There were 5 reports (0.9%) of increased postprocedural pain and 1 report (0.2%) of increased paresthesia/numbness to laser site. Three instances (0.6%) of increased erythema and 4 reports (0.7%) of epidermal sloughing or blistering were reported. All but 5 patients (2.9%) reported improvements to scar symptoms. This study demonstrates minimal adverse events associated with FCL for hypertrophic burn scar treatment.


Assuntos
Queimaduras , Cicatriz Hipertrófica , Terapia a Laser , Lasers de Gás , Masculino , Feminino , Humanos , Cicatriz Hipertrófica/etiologia , Cicatriz Hipertrófica/radioterapia , Cicatriz Hipertrófica/cirurgia , Estudos Retrospectivos , Resultado do Tratamento , Hipertrofia , Terapia a Laser/efeitos adversos , Dor , Queimaduras/complicações , Queimaduras/cirurgia , Lasers de Gás/uso terapêutico
10.
Artigo em Chinês | MEDLINE | ID: mdl-37805770

RESUMO

Objective: To investigate the surgical methods and clinical effects of free superficial peroneal artery perforator flap in repairing small and medium-sized thermal crush injury wounds in the hand. Methods: A retrospective observational study was conducted. From August 2018 to December 2021, 12 patients (19 wounds) with small and medium-sized thermal crush injury in the hand who met the inclusion criteria were hospitalized in Suzhou Ruihua Orthopaedic Hospital, including 5 males and 7 females, aged from 30 to 54 years. The area of the wound was from 2.5 cm×2.0 cm to 14.0 cm×3.5 cm, and all the wounds were repaired by using free superficial peroneal artery perforator flaps from lower leg on one side (including single flap, multiple flaps, and multiple flaps with one pedicle resected from the same donor site). The area of the flap was from 3.5 cm×3.0 cm to 16.0 cm×4.0 cm. The wound in the donor site was sutured directly. The vascular crisis and survival of the flap were observed after operation. The texture, appearance, color, hyperpigmentation, sensation, and two-point discrimination of the flap repaired area were followed up, as well as the hyperplasia of scar and pain condition in the donor and recipient sites. At the last follow-up, the curative effect of flap repair was evaluated by the comprehensive evaluation scale, and the extension and flexion functions of the reserved digital joint were evaluated by the total active movement systematic evaluation method recommended by American Academy for Surgery of Hand. Results: One flap developed arterial crisis on the first day after operation but survived after timely exploration. The other 18 flaps survived successfully after operation. Follow-up of 4 to 24 months after operation showed good texture and appearance in the flap repaired area; the color of the flap repaired area was similar to that of the normal skin around the recipient site, without pigmentation; the protective sensation was restored in all cases, but there was no two-point discrimination; there was no obvious hypertrophic scarring or pain in the donor or recipient site. At the last follow-up, the curative effect of flap repair was evaluated with 3 flaps being excellent and 16 flaps being good; the extension and flexion functions of the reserved digital joint were also assessed, being excellent in 8 fingers, good in 9 fingers, and fair in 2 fingers. Conclusions: The blood supply of superficial peroneal artery perforator flap is sufficient and reliable, and multiple flaps of this type or multiple flaps with one pedicle can be resected from one donor site. The use of this flap to repair small and medium-sized thermal crush injury wounds in the hand results in minimal damage to the donor area, and good postoperative appearance and texture of the flap.


Assuntos
Queimaduras , Cicatriz Hipertrófica , Lesões por Esmagamento , Retalho Perfurante , Procedimentos de Cirurgia Plástica , Lesões dos Tecidos Moles , Feminino , Humanos , Masculino , Artérias , Queimaduras/cirurgia , Cicatriz Hipertrófica/cirurgia , Lesões por Esmagamento/cirurgia , Dor , Retalho Perfurante/irrigação sanguínea , Transplante de Pele , Lesões dos Tecidos Moles/cirurgia , Resultado do Tratamento , Estudos Retrospectivos
11.
Artigo em Chinês | MEDLINE | ID: mdl-37805768

RESUMO

Objective: To explore the feasibility and clinical effects of using superficial temporal artery lobulated perforator flaps in repairing skin and soft tissue defects after tumor resection in the temporal region. Methods: A retrospective observational study method was used. From March 2017 to October 2022, ten patients with temporal skin tumors were admitted to the Affiliated Hospital of Zunyi Medical University, including six women and four men, with age ranging from 42 to 87 years. Among them, three patients had squamous cell carcinoma and seven patients had basal cell carcinoma, with disease duration ranging from 6 months to 5 years. All temporal tumors underwent expanded resection, leaving wound areas of 5.4 cm×4.2 cm to 7.0 cm×4.0 cm after tumor resection. Superficial temporal artery frontal branch flaps with areas of 5.5 cm×1.2 cm to 7.0 cm×1.5 cm, superficial temporal artery descending branch flaps with areas of 4.2 cm×3.5 cm to 5.0 cm×4.0 cm, and superficial temporal artery parietal branch flaps with areas of 4.2 cm×1.0 cm to 5.0 cm×1.0 cm were designed to repair the wounds and reconstruct the hairline. The donor areas of the flaps were closed and sutured directly. The survival of the flaps was observed on 3 to 5 days after surgery, and the healing of wounds on the donor and recipient sites was observed when the stitches were removed on 5 to 7 days after surgery. During follow-up after surgery, the appearance of the temporal area, scar hyperplasia, hairline reconstruction, and tumor recurrence were observed in the temporal region on the affected side. Results: All the flaps survived well on 3 to 5 days after surgery, and all the donor and recipient site wounds healed well on 5 to 7 days after surgery. During follow-up of 3 to 6 months after surgery, the surgical incisions were concealed; the flaps were not swollen, with a consistent color to the surrounding skin; there were no obvious hypertrophic scars; the reconstructed hairline on the affected side was not significantly different from that of the healthy side; there was no tumor recurrence in the local area. Conclusions: For large areas of skin and soft tissue defects in the temporal region, the use of superficial temporal artery lobulated perforator flaps can repair the wounds in different regions and suture the donor sites in the primary stage simultaneously. The surgical operation is simple, and the facial appearance conforms to the aesthetic requirement after surgery with no tumor recurrence in the local area but a good repair effect. This method is particularly suitable for repairing large areas of skin and soft tissue defects in the temporal region in elderly patients.


Assuntos
Cicatriz Hipertrófica , Retalho Perfurante , Procedimentos de Cirurgia Plástica , Lesões dos Tecidos Moles , Masculino , Humanos , Feminino , Idoso , Adulto , Pessoa de Meia-Idade , Idoso de 80 Anos ou mais , Retalho Perfurante/irrigação sanguínea , Artérias Temporais/cirurgia , Lesões dos Tecidos Moles/cirurgia , Recidiva Local de Neoplasia/cirurgia , Transplante de Pele , Cicatriz Hipertrófica/cirurgia , Resultado do Tratamento
12.
Phys Med Rehabil Clin N Am ; 34(4): 883-904, 2023 11.
Artigo em Inglês | MEDLINE | ID: mdl-37806704

RESUMO

More than 11 million burn injuries occur each year across the world. Many people with burn injuries, regardless of injury size, develop hypertrophic scar, contracture, unstable scar, heterotopic ossification, and disability resulting from these sequelae. Advances in trauma systems, critical care, safe surgery, and multidisciplinary burn care have markedly improved the survival of people who have experienced extensive burn injuries. Burn scar reconstruction aims to improve or restore physical function, confidence, and body image. Like acute burn care, burn scar reconstruction requires thoughtful, coordinated approaches along the continuum of burn injury, recovery, and rehabilitation.


Assuntos
Queimaduras , Cicatriz Hipertrófica , Contratura , Humanos , Cicatriz Hipertrófica/cirurgia , Cicatriz Hipertrófica/complicações , Queimaduras/complicações , Contratura/cirurgia , Contratura/complicações
13.
J Plast Reconstr Aesthet Surg ; 85: 226-234, 2023 10.
Artigo em Inglês | MEDLINE | ID: mdl-37524035

RESUMO

BACKGROUND: Inferior-central pedicle has some aesthetic drawbacks, including hypertrophic scar along the inframammary fold (IMF), squaring of the breast contours, and propensity to develop long-term 'bottoming-out.' This study aimed to verify if the narrow inferior-central (NIC) septum-based pedicle can allow the surgeon to improve aesthetic outcomes compared with the traditional inferior-central pedicle approach. METHODS: Forty breasts underwent NIC-based breast reduction (group A), and 37 underwent traditional inferior-central pedicles (group B). The NIC pedicle was drawn with a width of 3.5-4.5 cm. The recorded measurements were sternal notch to nipple distance (S-N) and nipple to IMF distance (N-IMF) at the time of preoperative markings and follow-up 1, 6, and 18 months after the procedure. RESULTS: The two groups were homogeneous regarding demographics, operative data, and preoperative S-N and N-IMF distances. Both groups showed no total or partial nipple-areola necrosis. At the 18-month follow-up, S-N (p < 0.00001) and N-IMF (p = 0.00039) distances were statistically different between the two groups, in favour of NIC group A. Changes in N-IMF distances between the 1- and 18-month visits were statistically different among groups (p < 0.0001), with a length variation of + 17.51% and + 28.46%, respectively. Patient satisfaction rate regarding "breast shape" (p = 0.021), "lower pole appearance" (p = 0.00017), and "scar" (p = 0.047) were higher in group A. CONCLUSION: NIC-based pedicle proved to be a safe procedure and allowed us to overcome limitations that typically characterise the inferior pedicle, i.e., 'bottoming-out' deformity, hypertrophic scar of the lower pole, and squaring of the breast contours. LEVEL OF EVIDENCE: II.


Assuntos
Cicatriz Hipertrófica , Mamoplastia , Humanos , Estudos de Coortes , Seguimentos , Cicatriz Hipertrófica/cirurgia , Resultado do Tratamento , Estudos Retrospectivos , Retalhos Cirúrgicos/cirurgia , Hipertrofia/cirurgia , Mamoplastia/métodos , Mamilos/cirurgia , Estética
14.
Am J Case Rep ; 24: e939022, 2023 Jun 05.
Artigo em Inglês | MEDLINE | ID: mdl-37276191

RESUMO

BACKGROUND Hypertrophic scars from severe burns cause physical and psychological stress. Proper treatment, including CO2 laser systems, can alleviate these burdens by enabling skin remodeling and collagen production. This study assessed the efficacy of a new laser device with 2 wavelengths (10 600 nm/1540 nm) and 2 scanning units on hypertrophic burn scar management. CASE REPORT A 34-year-old African woman sought treatment for a large hypertrophic burn scar on her right foot. The scar, formed at age 9, was complicated by infection. She underwent 2 CO2 sessions (Scar3 scanner), followed by 3 cycles of fractional CO2 +1540 nm laser (µScan DOT scanner) once a month, combined with topical hyaluronic acid. She also had 2 maintenance sessions with a 595-nm dye laser to prevent scar reactivation. The CO2 and 1540 nm laser synergy improved laxity through volumetric thermal effects, causing contraction and stimulation. This led to a softer, smaller scar with less consistency. The patient experienced significant improvement in quality of life due to alleviation of pain and restored footwear comfort. CONCLUSIONS The hypertrophic burn scar was effectively treated using 10 600 nm and 1540 nm wavelengths, along with dye laser treatment for recurrence prevention.


Assuntos
Queimaduras , Cicatriz Hipertrófica , Terapia a Laser , Lasers de Gás , Feminino , Humanos , Criança , Adulto , Cicatriz Hipertrófica/etiologia , Cicatriz Hipertrófica/cirurgia , Cicatriz Hipertrófica/patologia , Resultado do Tratamento , Qualidade de Vida , Dióxido de Carbono , Hipertrofia , Queimaduras/complicações , Queimaduras/cirurgia , Lasers de Gás/uso terapêutico , Terapia a Laser/efeitos adversos
17.
Surg Clin North Am ; 103(3): 515-527, 2023 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-37149387

RESUMO

This chapter highlights the importance of a comprehensive burn scar treatment plan in approaching a burn survivor. General concepts of burn scar physiology and a practical system to describe burn scars based on cause, biology, and symptoms are presented. Common scar management modalities including nonsurgical, surgical, and adjuvant therapies are further discussed.


Assuntos
Queimaduras , Cicatriz Hipertrófica , Procedimentos de Cirurgia Plástica , Cirurgia Plástica , Humanos , Cicatriz Hipertrófica/etiologia , Cicatriz Hipertrófica/cirurgia , Terapia Combinada , Queimaduras/complicações , Queimaduras/cirurgia
18.
J Dermatolog Treat ; 34(1): 2202287, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-37070799

RESUMO

BACKGROUND AND OBJECTIVES: Hypertrophic scarring is a complex process, and numerous methods have been introduced to treat scars. This study aims to evaluate the effect of combined CO2 fractional laser and narrowband intense pulsed light (IPL) compared to IPL alone in the treatment of hypertrophic scars. MATERIALS AND METHODS: This was a prospective, randomized controlled study enrolled 138 patients with hypertrophic scars. The participants were randomly divided into two groups: CO2-IPL and IPL group, and received three sessions at 10-14-week intervals for 3-month follow-up. Two independent plastic surgeons evaluated the treatments using the Patient and Observer Scar Assessment Scales (POSAS). Overall satisfaction was evaluated using the Patient Satisfaction Scale (PSS). RESULTS: 101 subjects completed the study. Compared to single IPL, the combination CO2-IPL group showed a significant improvement in itching, color, stiffness, thickness, and irregularity, except for pain, and an enhancement in vascularization, pigmentation, thickness, relief, and pliability of the scar, assessed by POSAS (p < .01). 100% patients in the combination group were satisfied compared to 84% in IPL alone. CONCLUSION: The combination of CO2 fractional laser and narrowband IPL efficiently improved the appearance and profile of hypertrophic scars, offering a comprehensive and reliable approach for scar therapy.


Assuntos
Cicatriz Hipertrófica , Lasers de Gás , Humanos , Cicatriz Hipertrófica/radioterapia , Cicatriz Hipertrófica/cirurgia , Cicatriz Hipertrófica/patologia , Cicatriz/terapia , Dióxido de Carbono , Resultado do Tratamento , Estudos Prospectivos , Lasers de Gás/uso terapêutico
19.
Lasers Surg Med ; 55(5): 471-479, 2023 07.
Artigo em Inglês | MEDLINE | ID: mdl-37051876

RESUMO

BACKGROUND: Laser treatments have been used to treat a variety of scar symptoms, including the appearance of scars following burn injury. One such symptom is hyperpigmentation. There are several qualitative and quantitative measures of assessing improvement in hyperpigmentation over time. The Patient and Observer Scar Assessment Scale (POSAS) and Vancouver Scar Scale (VSS) are two scales that describe characteristics of scar such as pigmentation level. These scales are limited by their qualitative nature. On the other hand, spectrophotometers provide quantitative measures of pigmentation. Prior studies have reported that laser can change scar pigmentation, but no quantitative values have been reported. The current study examines changes in scar melanin index after CO2 fractional ablative laser scar revision (FLSR) via noninvasive probe measurement in patients of various Fitzpatrick skin types (FST). MATERIALS AND METHODS: Patients with scars of various sizes and etiologies were treated with FLSR. A database was constructed including 189 patients undergoing laser treatment. From this pool, individuals were selected based on the criteria that they completed at least two laser sessions and had Melanin index measurements for both of these sessions and the pre-operative visit. This criteria resulted in 63 patients of various FST in the cohort. Melanin index, POSAS-Observer (O) and -Patient (P) pigmentation and color scores and VSS-pigmentation scores were examined over time. Demographic information (age of patient at time of first treatment, age of scar at time of first treatment, use of laser-assisted drug delivery (LADD), gender, FST, and Ethnicity) were collected from the medical record. Patients were grouped as "responder" if their Melanin index indicated decreased levels of hyperpigmentation after FLSR treatment in more than half of their total number of visits and "nonresponder" if it did not. RESULTS: The majority of patients were responders (41/63). In responder patients, measurements of Melanin index showed significantly improved levels of hyperpigmentation in hypertrophic scars after two FLSR sessions (p < 0.05). Age of patient, gender, FST, age of scar, ethnicity, or type of drug delivered by LADD did not predict responder grouping. POSAS-O and -P pigmentation/color scores showed improved scores after two FLSR sessions within the responder group. POSAS-P color scores showed improved scores after two and three FLSR sessions in the nonresponder group. VSS pigmentation scores showed improved scores after three FLSR sessions in the responder group only. CONCLUSION: Based on Melanin index values, FLSR leads to improvements in hyperpigmentation in certain patients.


Assuntos
Queimaduras , Cicatriz Hipertrófica , Hiperpigmentação , Lasers de Gás , Humanos , Cicatriz/etiologia , Cicatriz/terapia , Cicatriz/patologia , Cicatriz Hipertrófica/etiologia , Cicatriz Hipertrófica/cirurgia , Preparações Farmacêuticas , Melaninas , Resultado do Tratamento , Hipertrofia/complicações , Lasers de Gás/uso terapêutico , Hiperpigmentação/etiologia , Hiperpigmentação/terapia , Queimaduras/complicações
20.
J Craniofac Surg ; 34(4): e376-e380, 2023 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-36944605

RESUMO

BACKGROUND: Although early debridement and refining plastic surgery techniques have been shown to be effective in the treatment of facial scars after trauma, their postoperative outcomes have not been quantitatively evaluated by the relevant Scar Cosmesis Assessment and Rating (SCAR) Scale. This study was designed to provide a fair assessment of the appearance and local symptoms of scars after treatment by refining plastic surgery techniques and to share the operational skills of surgical repairs. PATIENTS AND METHODS: Patients who received refining plastic surgery techniques were followed up, and facial scars were taken as high-definition photos, which were presented to 6 professional observers, 6 lay observers, and patients themselves to score the facial scars, including: scar spread, erythema, dyspigmentation, track marks or suture marks, hypertrophy/atrophy, itch and pain according to the SCAR. RESULTS: There were 56 patients who met the inclusion criteria and 25 agreed to participate in the study. No hypertrophic scar was found, and all patients were satisfied with the scar control effect. The scores showed that the treatment was achieved good results in scar spread (pro group: 0.85±0.55, lay group: 0.96±0.68, patients: 0.92±0.64), erythema (pro group: 0.34±0.26, lay group: 0.45±0.37, patients: 0.32±0.48), hypertrophy/atrophy (pro group: 0.21±0.27, lay group: 0.21±0.31, patients: 0.32±0.48), and there was no significant difference in the scores of the 3 observation groups ( P >0.05). However, it is difficult to eliminate dyspigmentation (pro group: 0.29±0.26, lay group: 0.30±0.30, patients: 0.40±0.50), track marks or suture marks (pro group: 0.45±0.33, lay group: 0.59±0.30, patients: 0.36±0.49). Two (8%) patients complained of itch and 1 (4%) patient complained of both itch and pain in the past 24 hours. CONCLUSIONS: The appearance of facial scars is satisfactory, the local symptoms are mild, and the evaluation among different aesthetics is affirmative after receiving refining plastic surgery techniques, which is just in line with the purpose of seeking beauty for the patients, and meanwhile can provide a good foundation for the comprehensive treatment of late scars, so that the treatment plan should be promoted.


Assuntos
Cicatriz Hipertrófica , Traumatismos Faciais , Cirurgia Plástica , Humanos , Cicatriz/cirurgia , Cicatriz/patologia , Seguimentos , Cicatriz Hipertrófica/etiologia , Cicatriz Hipertrófica/cirurgia , Traumatismos Faciais/cirurgia , Hipertrofia , Dor , Eritema , Atrofia , Resultado do Tratamento
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